Edward G. Robinson
Dr. T.S. Clitterhouse
Claire Trevor
Jo Keller
Humphrey Bogart
'Rocks' Valentine
Allen Jenkins
Okay
Donald Crisp
Police Inspector Lewis Lane
Gale Page
Nurse Randolph
Henry O'Neill
Judge
John Litel
Mr. Monroe, Prosecuting Attorney
Thurston Hall
Grant
Ward Bond
Tug
Ronald Reagan
Radio Announcer (voice) (uncredited)
Mary Field
Millie - Mrs. Updyke's Maid (uncredited)
Maxie Rosenbloom
Butch
Vladimir Sokoloff
Popus