David Duchovny
Dr. Ira Kane
Julianne Moore
Dr. Allison Reed, CDC
Orlando Jones
Prof. Harry Phineas Block
Seann William Scott
Wayne Grey
Ted Levine
General Russell Woodman
Dan Aykroyd
Governor Lewis
Ty Burrell
Colonel Flemming
Andrew Bowen
Road Worker
Sarah Silverman
Denise
Katharine Towne
Nadine
Stephanie Hodge
Jill Mason
Gregory Itzin
Cartwright
Michelle Wolff
Carla
Steven Gilborn
Judge Guilder
Wayne Duvall
Dr. Paulson
Kyle Gass
Officer Drake
Jerry Trainor
Tommy
Jennifer Savidge
Clare
Wendy Braun
Nurse Tate
Michael Chapman
Sheriff Long
Ethan Suplee
Deke
Michael Bower
Danny
Mary Pat Gleason
Customer
John Cho
Student
Chris Wylde